98国产精品综合一区二区三区丨婷婷四房播播丨日日天干夜夜狠狠爱丨亚洲国产a∨无码中文777丨色琪琪丁香婷婷综合久久

信帆生物-轉錄因子COUP1抗體使用詳情

別    名Chicken ovalbumin upstream promoter 1; chicken ovalbumin upstream promoter; COT1_HUMAN; COUP transcription factor 1; COUP transcription factor I; COUP-TF I; COUP TF1; EAR-3; EAR3; ERBAL3; NR2F1; Nuclear receptor subfamily 2 group F member 1; SVP44; TCFCOUP1; TFCOUP1; Transcription factor COUP 1; V ERBA related protein EAR 3; V-erbA-related protein 3.  

抗體來源Rabbit

克隆類型Polyclonal

交叉反應Rat,  (predicted: Human, Mouse, Pig, Cow, Sheep, )

產品應用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

分 子 量46kDa

細胞定位細胞核 

性    狀Liquid

濃    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human COUP-TF1:21-120/423 

亞    型IgG

純化方法affinity purified by Protein A

儲 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed

產品介紹COUP transcription factors have been cloned in several species and identified as orphan members of the steroid/thyroid hormone receptor superfamily. COUP-TFI (also designated COUP or EAR-3) and ARP-1 (also designated COUP-TFII) exhibit highly regulated and overlapping expression in most tissues. COUP-TFs are highly expressed in the developing and central nervous system, suggesting that these factors may be important in neural development and differentiation. COUP-TFs can compete for binding to response elements which are common to other members of this family, including RAR, RXR, PPAR, HNF-4, VDR and TR. They have been shown to act as negative regulators as well as initiators of transcription.

Function:
Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. Represses transcriptional activity of LHCG.